BIOTECHNOLOGY USE CASE

For a biotech in GUT-MICROBIOME THERAPEUTICS

Biotechnology use case

R E Q U I R E M E N T

EXPLORE the existence of metagenomic signatures that would be predictive of a response to a developed drug for inflammatory bowel disease patients in a Phase IIa clinical trial

S E R V I C E S  P R O V I D E D

  • AGGREGATE data from more than 900 metagenomic signatures with clinical variables (Gender, Weight…) on 40 patients
  • DEVELOP univariate methodology to keep relevant metagenomic signatures and clinical variables in the global model
  • IMPLEMENT appropriate supervised Machine Learning algorithms for prediction of response/non-response
  • COMPARE & CHOOSE the best algorithm for prediction using bootstrap and cross-validation
  • IDENTIFY metagenomic signatures and clinical variables best explaining response/non-response to the treatment

D E L I V E R A B L E S  &  B E N E F I T S

PREDICTIVE MODEL for the response/non-response of patients

REPORT summarizing the methodology used, the algorithms developed and the results obtained

Requirement

EXPLORE the existence of metagenomic signatures that would be predictive of a response to a developed drug for inflammatory bowel disease patients in a Phase IIa clinical trial

Services provided

  • AGGREGATE data from more than 900 metagenomic signatures with clinical variables (Gender, Weight…) on 40 patients
  • DEVELOP univariate methodology to keep relevant metagenomic signatures and clinical variables in the global model
  • IMPLEMENT appropriate supervised Machine Learning algorithms for prediction of response/non-response
  • COMPARE & CHOOSE the best algorithm for prediction using bootstrap and cross-validation
  • IDENTIFY metagenomic signatures and clinical variables best explaining response/non-response to the treatment

Deliverables  & benefits

PREDICTIVE MODEL for the response/non-response of patients

REPORT summarizing the methodology used, the algorithms developed and the results obtained

Biopharmaceutics use case
Biotechnology use case
Animal health use case
Digital therapeutics use case
Cosmetics use case
Agrifood use case
Urbanism use case
Energy use case
Logo Soladis Group by EFOR transparent 45

Soladis Inc. - USA
185 Alewife Brook Pkwy, Unit 210
Cambridge, MA 02138-1100

Phone: (+1)347.417.4008

    CONTACT US


    Before sending, please copy this code captcha

    in this field:

    SEARCH

    MENU

    MENU

    Suscribe to our newsletter

    Biopharmaceutics use caseAnimal health use case

    En cliquant sur le lien ci-dessous, vous allez être redirigé vers LinkedIn. Des cookies tiers peuvent alors être installés sur votre navigateur. Ces cookies ne sont pas implémentés directement par le site Soladis mais par le site de réseau social auquel vous vous connectez.
    Ces cookies sont soumis à leurs propres politiques de confidentialité et ne relèvent en aucun cas de la responsabilité de Soladis.
    Vous pouvez consulter la politique de LinkedIn en matière de cookies en cliquant sur le lien suivant : LinkedIn – Politique relative aux cookies

      Suivre Soladis sur LinkedIn

    En cliquant sur le lien ci-dessous, vous allez être redirigé vers Youtube. Des cookies tiers peuvent alors être installés sur votre navigateur. Ces cookies ne sont pas implémentés directement par le site Soladis mais par le site auquel vous vous connectez.
    Important : ces cookies sont soumis à leurs propres politiques de confidentialité et ne relèvent en aucun cas de la responsabilité de Soladis.
    Vous pouvez consulter la politique de Youtube en matière de cookies en cliquant sur le lien suivant : Google – Règles de confidentialité et conditions d’utilisation

      Suivre Soladis sur Youtube

    By clicking on the link below, you will be redirected to LinkedIn. Third-party cookies may then be installed on your browser. These cookies are not implemented directly by the Soladis site but by the social network site to which you connect.
    These cookies are subject to their own privacy policies and are in no way the responsibility of Soladis.
    You can view LinkedIn's cookie policy by clicking on the following link :  LinkedIn – Cookie Policy

    Follow Soladis on LinkedIn

    By clicking on the link below, you will be redirected to Youtube. Third-party cookies may then be installed on your browser. These cookies are not implemented directly by the Soladis site but by the site to which you connect.
    Important: these cookies are subject to their own privacy policies and are in no way the responsibility of Soladis.
    You can view Youtube's cookie policy by clicking on the following link: Google – Privacy & terms

      Follow Soladis on Youtube